Project Manager

Manager of Quality Assurance

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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>You will contribute by:</strong></p>
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<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">1. Use artificial intelligence to solve key sub-problems in the process of new drug development;</span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">2. Explore cutting-edge technologies in academia and industry to realize the development of algorithm prototypes;</span></p>
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<p class="paragraph text-align-type-left pap-line-1.3 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt">3. Participate in systems design, develop and refine them</p>
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<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译">&nbsp;</p>
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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>For this position you&rsquo;ll need the following&nbsp;education, experience&nbsp;and&nbsp;skills:</strong></p>
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<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">1. Bachelor degree or above in CS or other related major;</span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">2. Solid foundation, familiar with at least one programming language (Java, Python, C/C++, etc.);</span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">3. Master at least one deep learning framework (tensorflow, pytorch, etc.);</span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">4. More than 3 years of relevant work experience.</span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译">&nbsp;</p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><strong><span class="Y2IQFc" lang="en">These will be preferred:</span></strong></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">1. Master's degree or above in artificial intelligence or other related majors;</span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">2. Published papers in top AI journals;</span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">3. Received honors from ACM or other competitions;</span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">4. Have a broad vision in the field of AI, and have unique insights into multiple segments of AI;</span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">5. Have experience in AI team management, and have the ability to quickly solve abstract problems.</span></p>

Senior Scientist for AI Aided Drug Design (AIDD)

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<p>You are a dynamic and experienced clinical leader who can drive strategy and execution of ongoing and future clinical trials.</p>
<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>You will contribute by:</strong></p>
<p>1. Develop and execute worldwide clinical study strategy including management of ongoing multicenter, single arm and randomized controlled trials as well as outlining needs and prioritization of future clinical studies.</p>
<p>2. Serve as Executive Leadership Team member through collaboration on corporate strategy, operating plan / budget development, and corporate culture development. Serve as clinical expert in strategic meetings and consistent reporting to Board of Directors.</p>
<p>3. Establish and manage effective plans for study planning and execution including models for predicting study cadence, resource needs, key metrics to track progress and tools to ensure all activities are accounted for.</p>
<p>4. Effectively create and meet department budget resource management, IRB/EC submissions, legal agreements with sites, purchasing, protocol execution, compliance, and contracting.</p>
<p>5. Ensure compliance to study protocols, domestic and international Good Clinical Practices, applicable regulatory standards, and Zenflow&rsquo;s Standard Operating Procedures.</p>
<p>6. Develop clinical protocols, statistical plans, investigator&rsquo;s brochures, ICFs, CRFs, monitoring plans, clinical reports, and other documents.</p>
<p>7. Build and manage relationships with clinicians including Scientific Advisory Board, KOLs, and investigators in order to develop clinical strategies, protocols, analysis and study execution.</p>
<p>8. Contract and oversee CROs as required, managing costs and tracking deliverables.</p>
<p>9. Effectively manage a growing clinical team and help determine optimal hiring strategy.</p>
<p>10. Draft clinical components of regulatory submissions.</p>
<p>11. Operate as a team player in a fast-moving clinical-stage startup, keeping time and cost efficiency top of mind.</p>
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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>For this position you&rsquo;ll need the following education, experience and skills:</strong></p>
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<p>1. Ph.D. or M.D. degree required in metabolism disease or related fields;</p>
<p>2. Proficient in clinical trial process and related regulations, with clinical drug development, trial management and other related experience;</p>
<p>3. Have more than 7 years of relevant work experience in the field of metabolism disease. A certain academic influence in the industry is preferred;</p>
<p>4. Work experience in multinational pharmaceutical companies or well-known R&amp;D institutions is preferred;</p>
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Director/Senior Director/VP, Clinical Research

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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>You will contribute by:</strong></p>
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<p>Participate in literature and patent research to provide basis for new drug research and development projects;</p>
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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>For this position you&rsquo;ll need the following&nbsp;education, experience&nbsp;and&nbsp;skills:</strong></p>
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<p>1. Bachelor degree or above in medicinal chemistry, computational chemistry, computational biology and other related majors;</p>
<p><span class="jCAhz ChMk0b"><span class="ryNqvb">2. Have good communication skills and teamwork spirit, and have good English speaking and reading skills;</span></span></p>
<p><span class="jCAhz ChMk0b"><span class="ryNqvb">3. Those who can use Shell, Python and other programming are preferred;</span></span></p>
<p><span class="jCAhz ChMk0b"><span class="ryNqvb">4. Sense of responsibility, and teamwork spirit;</span></span></p>

Internship, Medical Chemistry Research

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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>You will contribute by:</strong></p>
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<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">1. Solve key sub-problems related to the new drug development process based on machine learning methods, such as biological/pharmaceutical small molecule generation, virtual screening, etc.; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">2. Read relevant cutting-edge scientific and technological papers, reproduce the methods in the papers, and try to improve and innovate to realize the development of algorithm prototypes; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">3. Integrate existing algorithm prototypes into the system to complete the development of related system modules; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译">&nbsp;</p>
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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>For this position you&rsquo;ll need the following&nbsp;education, experience&nbsp;and&nbsp;skills:</strong></p>
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<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en"> 1. Bachelor degree or above in computer, informatics, physics, biomedical engineering and other related majors; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">2. Solid basic computer knowledge, proficient in common data structures and algorithms; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">3. Have strong coding ability and experience in data competition is preferred; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">4. Proficient in using python and familiar with Linux environment; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">5. Familiar with the basic theory of machine learning and deep learning, familiar with commonly used time series models and graph network models, including but not limited to RNN/LSTM, GCN, etc., familiar with Transformer, GPT, BERT, etc.; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">6. Proficiency in at least one deep learning framework: TensorFlow/Keras/pytorch; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">7. Cheerful personality, sense of responsibility, and teamwork spirit; </span></p>

Internship, AI Drug Discovery

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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>You will contribute by:</strong></p>
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<p><span class="Y2IQFc" lang="en">1. Conduct in-depth research on disease areas, clinical needs and drug targets,; </span></p>
<p><span class="Y2IQFc" lang="en">2. Responsible for the collection and sorting of domestic and foreign medical information, project initiation and research, and writing project feasibility research reports; </span></p>
<p><span class="Y2IQFc" lang="en">3. From the perspective of biology, conduct in-depth analysis of the company's proposed project, evaluate the drugability of the target, and provide decision-making suggestions; </span></p>
<p><span class="Y2IQFc" lang="en">4. Searching and summarizing domestic and foreign medical literature, patents and drug-related information; </span></p>
<p><span class="Y2IQFc" lang="en">5. In-depth study of target biology, signal transduction pathway, and mechanism of action; determine the molecular form of the drug to be developed; </span></p>
<p><span class="Y2IQFc" lang="en">6. Design, implement and analyze in vitro and in vivo mechanism of action experiments to provide data support for the confirmation of candidate drug molecules; </span></p>
<p><span class="Y2IQFc" lang="en">7. Responsible for the collection, arrangement and analysis of the technical data of the products under research, patent and technology project declaration, foreign academic exchanges, etc.; support the analysis and evaluation of the market and competition pattern; </span></p>
<p><span class="Y2IQFc" lang="en">8. Complete other work arranged by the superior leader.</span></p>
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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>For this position you&rsquo;ll need the following&nbsp;education, experience&nbsp;and&nbsp;skills:</strong></p>
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<p id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">1. Molecular biology, cell biology and other related majors, doctoral degree, with more than 5 years of work experience in pharmaceutical companies/CRO; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">2. Those who have work experience in new drug research and development or project initiation research and application materials writing are preferred; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">3. Experience in cell experiments and animal experiments, leading biopharmaceutical research and development projects from target selection, verification to IND application is preferred, and working experience in large innovative companies in domestic and foreign industries is preferred; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">4. Have strong interpersonal communication skills, organizational skills and teamwork skills, and good project management skills; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">5. Possess the ability to explore literature and information, and have excellent English reading, writing and communication skills.</span></p>

Director/VP, Biology

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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>You will contribute by:</strong></p>
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<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">1. Use artificial intelligence to solve key sub-problems in the process of new drug development; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">2. Explore cutting-edge technologies in academia and industry to realize the development of algorithm prototypes; </span></p>
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<p class="paragraph text-align-type-left pap-line-1.3 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt">3. Participate in systems design, develop and refine them</p>
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<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译">&nbsp;</p>
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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>For this position you&rsquo;ll need the following&nbsp;education, experience&nbsp;and&nbsp;skills:</strong></p>
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<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">1. Bachelor degree or above in CS or other related major; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">2. Solid foundation, familiar with at least one programming language (Java, Python, C/C++, etc.); </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">3. Master at least one deep learning framework (tensorflow, pytorch, etc.); </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">4. More than 3 years of relevant work experience. </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译">&nbsp;</p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><strong><span class="Y2IQFc" lang="en">These will be preferred:</span></strong></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">1. Master's degree or above in artificial intelligence or other related majors; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">2. Published papers in top AI journals; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">3. Received honors from ACM or other competitions; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">4. Have a broad vision in the field of AI, and have unique insights into multiple segments of AI; </span></p>
<p class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="翻译"><span class="Y2IQFc" lang="en">5. Have experience in AI team management, and have the ability to quickly solve abstract problems.</span></p>

Senior Scientist, AI Drug Discovery 

<p><strong>You will contribute by:</strong></p>
<p>Lead our CADD team to develop and optimize our CADD tools and methods. In partnership with our CSO, our biology and chemistry teams and our AI algorithm team, your experience will help to complete project implementation, providing scientific excellence to influence and impact upon our drug discovery programs.</p>
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<p><strong>For this position you&rsquo;ll need the following&nbsp;education, experience&nbsp;and&nbsp;skills:</strong></p>
<p>1. Vision to design, develop and apply novel tools to the drug discovery process</p>
<p>2. Extensive experience in applying principles of structural biology and medicinal chemistry toward drug discovery</p>
<p>3. Experience in accelerating drug discovery through application of machine learning and data analytics/science would be attractive</p>
<p>4. Ability to influence and impact beyond immediate area of responsibility</p>
<p>5. A PhD in structural biology, chemistry, computational chemistry, molecular modeling or a related field is required with a good publication/patent track record</p>

Director/VP, Computer Aided Drug Design

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<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>You will contribute by:</strong></p>
<ol start="1" type="1">
<li data-id="po1igg" data-level="0" data-level-text="%1." data-order="0" data-format="STNumberFormat_decimal" data-type="Numbered">
<p class="paragraph text-align-type-left pap-line-1.4291666666666667 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt pap-left-indent-0pt pap-hanging-indent-16.8pt">Closely working across line functions to actively participating in nominating new frontier targets and establishing new drug discovery programs</p>
</li>
<li data-id="po1igg" data-level="0" data-level-text="%1." data-order="1" data-format="STNumberFormat_decimal" data-type="Numbered">
<p class="paragraph text-align-type-left pap-line-1.4291666666666667 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt pap-left-indent-0pt pap-hanging-indent-16.8pt">Participate in the entire process of new drug development, including target selection, patent cracking, R&amp;D node control, project management, etc.&nbsp;</p>
</li>
<li data-id="po1igg" data-level="0" data-level-text="%1." data-order="2" data-format="STNumberFormat_decimal" data-type="Numbered">
<p class="paragraph text-align-type-left pap-line-1.4291666666666667 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt pap-left-indent-0pt pap-hanging-indent-16.8pt">Identifying, establishing and leading partnerships with selected CRO partners focused on the design, synthesis and characterization of high-quality compounds.</p>
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<li data-id="po1igg" data-level="0" data-level-text="%1." data-order="3" data-format="STNumberFormat_decimal" data-type="Numbered">
<p class="paragraph text-align-type-left pap-line-1.4291666666666667 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt pap-left-indent-0pt pap-hanging-indent-16.8pt">Expanding the scope of our existing product pipeline projects</p>
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<h3 class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt">&nbsp;</h3>
<p class="paragraph text-align-type-left pap-line-1.7 pap-line-rule-auto pap-spacing-before-0pt pap-spacing-after-0pt"><strong>For this position you&rsquo;ll need the following&nbsp;education, experience&nbsp;and&nbsp;skills:</strong></p>
<ol start="1" type="1">
<li data-id="hu7w0w" data-level="0" data-level-text="%1." data-order="0" data-format="STNumberFormat_decimal" data-type="Numbered">
<p class="paragraph text-align-type-left pap-line-1.4291666666666667 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt pap-left-indent-0pt pap-hanging-indent-16.8pt">Ph.D. degree in chemistry with over 5 years&rsquo; experience in the pharmaceutical/biotech industry alongside a strong track record of scientific innovation in the medicinal chemistry discipline.</p>
</li>
<li data-id="hu7w0w" data-level="0" data-level-text="%1." data-order="1" data-format="STNumberFormat_decimal" data-type="Numbered">
<p class="paragraph text-align-type-left pap-line-1.4291666666666667 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt pap-left-indent-0pt pap-hanging-indent-16.8pt">Demonstrable track record of identifying, validating, and progressing lead compounds against challenging targets with a deep understanding of all aspects of hit and lead generation.</p>
</li>
<li data-id="hu7w0w" data-level="0" data-level-text="%1." data-order="2" data-format="STNumberFormat_decimal" data-type="Numbered">
<p class="paragraph text-align-type-left pap-line-1.4291666666666667 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt pap-left-indent-0pt pap-hanging-indent-16.8pt">Experience in leading and managing early discovery projects.</p>
</li>
<li data-id="hu7w0w" data-level="0" data-level-text="%1." data-order="3" data-format="STNumberFormat_decimal" data-type="Numbered">
<p class="paragraph text-align-type-left pap-line-1.4291666666666667 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt pap-left-indent-0pt pap-hanging-indent-16.8pt">Experience managing scientific collaborations and CRO outsourcing activities.</p>
</li>
<li data-id="hu7w0w" data-level="0" data-level-text="%1." data-order="4" data-format="STNumberFormat_decimal" data-type="Numbered">
<p class="paragraph text-align-type-left pap-line-1.4291666666666667 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt pap-left-indent-0pt pap-hanging-indent-16.8pt">A deep understanding of ADMET and PK and be able to use this knowledge skillfully to help solve problems in drug discovery.&nbsp;</p>
</li>
<li data-id="hu7w0w" data-level="0" data-level-text="%1." data-order="5" data-format="STNumberFormat_decimal" data-type="Numbered">
<p class="paragraph text-align-type-left pap-line-1.4291666666666667 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt pap-left-indent-0pt pap-hanging-indent-16.8pt">Extensive working knowledge of modern medicinal chemistry and drug discovery techniques.</p>
</li>
<li data-id="hu7w0w" data-level="0" data-level-text="%1." data-order="6" data-format="STNumberFormat_decimal" data-type="Numbered">
<p class="paragraph text-align-type-left pap-line-1.4291666666666667 pap-line-rule-auto pap-spacing-before-3pt pap-spacing-after-3pt pap-left-indent-0pt pap-hanging-indent-16.8pt">Innovative team-player with high energy for our fast-paced environment as a startup</p>
</li>
</ol>
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